Lyndon James hit a career-best 91 as Nottinghamshire set Lancashire a formidable target on day three of their LV= Insurance County Championship encounter.
James formed a fruitful partnership with Tom Moores (97) as the hosts declared on 339/8, a lead of 443.
In reply, Lancashire proceeded to 115/1 at stumps.
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Nottinghamshire's First-Class season at Trent Bridge concludes with the visit of Yorkshire (21-24 September), as Steven Mullaney's men hunt two red-ball trophies.
